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(2020) Origin, Distribution, and Biogeochemistry of Arsenic in the Altiplano-Puna Plateau of South America

Murray J, Tapia J, Ormachea M, Tirado N & Nordstrom K

https://doi.org/10.46427/gold2020.1871

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13g: Room 4, Wednesday 24th June 06:00 - 06:03

Listed below are questions that have been submitted by the community that the author will try and cover in their presentation. To submit a question, ensure you are signed in to the website. Authors or session conveners approve questions before they are displayed here.

Submitted by Karen Hudson-Edwards on Friday 19th June 11:02
Interesting and comprehensive study. What are your hypotheses on why local peoples do not show symptoms of arsenic poisoning?
The reason why these populations do not have symptoms and signs of arsenic poisoning is due to a genetic adaptation, that is, these populations have been exposed for hundreds of years and have genes for more effective and faster elimination of the arsenic that enters the body. Specifically these populations had a polymorphism of genes of key enzymes in charge of detoxification or elimination of arsenic such as the arsenic 3 methyl transferase (AS3MT), among others. This genetic adaptation was first found in woman from San Antonio de los Cobres, Argentina (where arsenic in drinking water was more than 200 micrograms per liter) and recently in woman from the Popoo lake area in Bolivia.

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